|Four player game|
The best aspects of this game are the flavor and replayability. There are so many different villains and hero decks that each game can play out vastly different then the next game. Each game offers a unique puzzle that everyone must work together to figure out.
This game has three major downsides in my mind. First, is the amount of time you spend waiting for other players to take their turn. As players become more accustomed to how to play the game the turns may speed up a bit, but if you take a quick turn you can be waiting a while before your next turn comes around. The second downside is how fiddley the game is. At times its really hard to remember how all the cards interact and affect one another. They have pieces to help alleviate this, but when each card is affected by a different card (or cards) and they're all dealing damage to different players based on different conditions...well something is bound to be missed. Finally, if you don't draw the correct cards you may not have any effect on the game. My deck was all about having guns, but I didn't draw a gun until turn 4. This meant that my first three turns were inconsequential. Doing nothing on your turn only compounds the feeling of waiting too long for everyone else on their turns.
Despite all my criticism I would recommend trying this at least once. Lots of people really love the game so it can't be all bad.